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Age-related hearing loss: the complex interaction of carbohydrate metabolism in auditory and cognitive dysfunction during aging

Abstract:
Age-related hearing loss (ARHL) is an extremely widespread form of age-related disease mainly characterized by high-frequency hearing loss and subsequent cognitive dysfunction. The pathological changes associated with ARHL involve both... MORE
Shengyu Zou, , ...Zuhong He,
Open Access Review DOI: 10.20517/and.2024.35 31 Mar 2025
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Circular RNAs modulate cancer drug resistance: advances and challenges

Abstract:
Acquired drug resistance is a main factor contributing to cancer therapy failure and high cancer mortality, highlighting the necessity to develop novel intervention targets. Circular RNAs (circRNAs), an abundant class of RNA molecules with... MORE
Jinghan Hua, ... Ping ZhaoPing Zhao
Open Access Review DOI: 10.20517/cdr.2024.195 27 Mar 2025
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Symbolic regression accelerates the discovery of quantitative relationships in rubber material aging

Abstract:
Polymer materials, especially rubber, play an indispensable role in modern life and manufacturing. However, their aging and deterioration pose serious challenges to their stability and service life. Unexpected aging can lead to the... MORE
Wentao LiWentao Li, ... Xiaonan Wang
Open Access Research Article DOI: 10.20517/jmi.2024.103 27 Mar 2025
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Uncertainty aware design space modeling for sample efficiency in material design of bainitic steels

Abstract:
Optimizing sampling efficiency is crucial for solving complex material design challenges, especially with a limited experimental budget. This study focuses on improving sampling efficiency by reducing the search space for carbide-free... MORE
Bernd SchuschaBernd Schuscha, ... Daniel ScheiberDaniel Scheiber
Open Access Research Article DOI: 10.20517/jmi.2024.90 27 Mar 2025
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Exosomal miR-92b-5p regulates N4BP1 to enhance PTEN mono-ubiquitination in doxorubicin-resistant AML

Abstract:
Aim: Doxorubicin, pivotal for acute myeloid leukemia (AML) treatment, often succumbs to resistance, impeding therapeutic success. Although exosomal transfer is linked to chemoresistance, the detailed role of exosomal miRNAs in... MORE
Qianyuan LiQianyuan Li, ... Chenjiao Yao
Open Access Original Article DOI: 10.20517/cdr.2024.140 27 Mar 2025
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Dual-channel event-triggered consensus of multi-agent systems under DoS attacks over switching topologies

Abstract:
In this paper, a dual-channel event-triggered control (ETC) protocol with a state estimator is designed in multi-agent systems with switching topologies under denial-of-service attacks. Firstly, an ETC protocol and a dynamic ETC protocol... MORE
Wenjie Li, ... Feng Zhao
Open Access Research Article DOI: 10.20517/ces.2024.104 27 Mar 2025
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The ion-ion correlations in organic ionic plastic crystal

Abstract:
Organic ionic plastic crystals (OIPCs) are emerging as promising electrolyte materials for solid-state batteries. However, despite the fast ionic diffusion, OIPCs exhibit relatively low DC conductivity in solid phases caused by strong... MORE
Md. Dipu Ahmed, ... Ivan PopovIvan Popov
Open Access Article DOI: 10.20517/energymater.2024.209 27 Mar 2025
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Zwitterionic gemini additive as interface engineers for long-life aqueous Zn/TEMPO flow batteries with enhanced areal capacity

Abstract:
Aqueous Zn-based flow batteries often face issues such as poor reversibility and short lifespan due to irregular Zn deposition and detrimental side reactions. To address these challenges, we developed a zwitterionic gemini additive,... MORE
Feiyang Hu, ... Jiangxuan Song
Open Access Article DOI: 10.20517/energymater.2024.161 27 Mar 2025
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Dual etiology vs. MetALD: how MAFLD and MASLD address liver diseases coexistence

Abstract:
Fatty liver disease associated with metabolic dysfunction has emerged as a significant global health challenge. This condition often coexists with other liver diseases, such as alcohol-related liver disease and viral hepatitis,... MORE
Shadi Zerehpooshnesfchi, ... Mohammed Eslam
Open Access Review DOI: 10.20517/mtod.2025.04 27 Mar 2025
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An effective fault-tolerant control with slime mold algorithm for unmanned underwater vehicle

Abstract:
The proposed fault-tolerant control strategy based on the slime mold algorithm (FTC-SMA) enhances the resilience of multi-thruster unmanned underwater vehicles against thrust loss. In the event of a propulsion system failure, the strategy... MORE
Tianhong Zeng, ... Simon X. Yang
Open Access Research Article DOI: 10.20517/ir.2025.14 26 Mar 2025
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Challenges in the management of MetALD after liver transplantation

Abstract:
Metabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-associated liver disease (ALD) are among the leading indications for liver transplantation (LT). The definition of metabolic dysfunction- and alcohol-associated... MORE
Monica Cucco, ... Luca Saverio Belli
Open Access Review DOI: 10.20517/mtod.2024.144 26 Mar 2025
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Thermal degradation of lithium-ion battery cathodes: a machine learning prediction of stability and safety

Abstract:
Lithium-ion batteries are extensively utilized due to their diverse applications, but their potential risk of thermal runaway leading to fire or even explosion... MORE
Yuxin Zhou, ... Xinyan HuangXinyan Huang
Open Access Article DOI: 10.20517/energymater.2024.200 26 Mar 2025
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Strategies to combat cancer drug resistance: focus on copper metabolism and cuproptosis

Abstract:
Cancer cells often develop tolerance to chemotherapy, targeted therapy, and immunotherapy drugs either before or during treatment. The significant heterogeneity among various tumors poses a critical challenge in modern cancer research,... MORE
Leyi Yao, ... Dacai Xu
Open Access Review DOI: 10.20517/cdr.2025.41 26 Mar 2025
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Achieving low carbon finance of the iron and steel industry in China

Abstract:
As a key sector characterized by high energy consumption and carbon emissions, the low-carbon transition of the iron and steel industry is crucial for achieving national emission reduction targets. Although China's iron and steel industry... MORE
Xuejing Jiang, Jingyu Liu
Open Access Commentary DOI: 10.20517/cf.2024.55 25 Mar 2025
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FT2DP: large atomic model fine-tuned machine learning potential for accelerating atomistic simulation of iron-based Fischer-Tropsch synthesis

Abstract:
Density-functional theory (DFT)-based atomistic simulation methods have been essential in studying the structure-property relationships in heterogeneous... MORE
Zhao-Qing LiuZhao-Qing Liu, ... Hong JiangHong Jiang
Open Access Research Article DOI: 10.20517/jmi.2024.105 25 Mar 2025
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A milestone for the therapeutic EV field: FDA approves Ryoncil, an allogeneic bone marrow-derived mesenchymal stromal cell therapy

Abstract:
Small extracellular vesicles (sEVs) derived from mesenchymal stromal cells (MSCs) hold substantial promise for therapeutic applications, including immune modulation and tissue regeneration. However, challenges such as batch-to-batch... MORE
Bernd Giebel
Open Access Commentary DOI: 10.20517/evcna.2025.02 25 Mar 2025
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A study on non-uniform image dehazing algorithm based on serialized integrated attention and multi-dimensional transformer

Abstract:
To address the issues of detail loss and blurred restoration in the non-uniform image dehazing process of existing non-uniformly hazy images, this paper presents a novel non-uniform image dehazing algorithm based on serialized integrated... MORE
Tianhao Bai, Ji QiuJi Qiu
Open Access Research Article DOI: 10.20517/ces.2024.95 24 Mar 2025
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Retrieve-then-compare mitigates visual hallucination in multi-modal large language models

Abstract:
Multi-modal large language models (MLLMs) demonstrate remarkable success in a range of vision-language tasks. However, they are prone to visual hallucinations, where their textual responses diverge from the provided image. Inaccurate... MORE
Dingchen Yang, ... Guang ChenGuang Chen
Open Access Research Article DOI: 10.20517/ir.2025.13 24 Mar 2025
Views: 85 Downloads: 30
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Inhalable exosomes to target cardiac repair

Abstract:
A recent study introduces Stem Cell-derived Exosome Nebulization Therapy (SCENT), a novel, non-invasive strategy that delivers lung spheroid cell-derived exosomes via inhalation to promote cardiac repair after myocardial infarction. This... MORE
Ajit MagadumAjit Magadum
Open Access Research Highlight DOI: 10.20517/evcna.2024.81 24 Mar 2025
Views: 97 Downloads: 30
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Robotic metabolic and bariatric surgery in community vs. academic centers in USA: a bibliometric analysis on behalf of TROGSS - The Robotic Global Surgical Society

Abstract:
Robotic metabolic and bariatric surgery (RMBS) has emerged as the most effective approach in the treatment of severe obesity in academic medical centers (AMCs) and community medical centers (CMCs) in the United States of America (USA).... MORE
Yeisson Rivero-MorenoYeisson Rivero-Moreno, ... Rodolfo J. OviedoRodolfo J. Oviedo
Open Access Review DOI: 10.20517/mtod.2024.90 24 Mar 2025
Views: 171 Downloads: 51
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