fig2

Figure 2. Colonisation with E. lenta had no significant effects on the host. (A) Weight of the caecum, body, liver, and total WAT as well as blood levels of fasting glucose and cholesterol. Data plotted as dots representing individual mice. Within each group, mice housed in different cages are indicated with empty or filled circles. Black bars show median values. Statistics: Kruskal-Wallis test followed by Dunn’s test for multiple comparisons. Stars indicate significant differences between diets (*adj. P < 0.05; **adj. P < 0.01); (B) PCA of liver proteomes per colonisation group (P = 0.582; PERMANOVA); (C) Same as in panel (B), shown per diet groups (P = 0.001; PERMANOVA). Panel (A) of this figure was published in the PhD thesis by co-author Theresa Streidl^[58]. WAT: White adipose tissue; PCA: principal component analysis; MM: mice colonised with the mouse synthetic community OMM12; E.L: mice colonised with OMM12 and Coriobacteriia; CD: control diet; CD-BA: control diet supplemented with 0.2% primary bile acids; HFD: lard-based high-fat diet; HFD-BA: HFD supplemented with 0.2% primary bile acids.