fig3
From: Percutaneous “edge-to-edge” leaflet repair in patients with secondary mitral valve regurgitation

Figure 3. Treatment option (OMT, TMVR) of functional MR in patients with disproportionate or proportionate severe MR according to EROA and LVEDV. Based on an analysis of subgroups of patients enrolled in the COAPT trial and the MITRA-FR trial by M. Packer and P.A. Grayburn[26]. EROA: effective regurgitant orifice area; LVEDV: left ventricular end-diastolic volume; MR: mitral regurgitation; TMVR: transcatheter mitral valve repair; OMT: optical medical therapy. Copyright of the figure belongs to Prof. Tarantini