fig1
From: Percutaneous “edge-to-edge” leaflet repair in patients with secondary mitral valve regurgitation
Figure 1. Underlying mechanisms of functional MR in HFrEF (A) and HFpEF (B). In HFpEF aortic stenosis may be one of the underlying conditions causing LV impaired relaxation and reduced shortening contraction. Other frequent conditions are diabetes mellitus and myocardial ischemic disease. Another possible condition is atrial fibrillation which, instead, directly causes LA functional and structural remodelling. MR: mitral regurgitation; LA: left atrium; LV: left ventricle; Ao: aorta
