Topic: The effects of xenobiotics on the human microbiome

The human microbiome plays a crucial role in maintaining health and metabolic homeostasis. However, exposure to xenobiotics—chemical substances foreign to the body, including pharmaceuticals, environmental pollutants, pesticides, and food additives—can significantly alter the composition and functionality of the microbiome. These changes may lead to dysbiosis, affecting immune responses, metabolic pathways, and overall health.

This special issue aims to explore the complex interactions between xenobiotics and the human microbiome, shedding light on their mechanisms of action, potential health impacts, and strategies to mitigate adverse effects. We welcome original research, reviews, and perspectives covering various aspects of this dynamic field, including but not limited to:

● The impact of pharmaceuticals and antibiotics on gut microbiota;

● Environmental pollutants and microbiome alterations;

● Metabolic transformations of xenobiotics by microbial communities;

● The role of diet and probiotics in mitigating xenobiotic-induced dysbiosis;

● Advances in microbiome-targeted therapeutic strategies.

This issue will provide a platform for researchers to contribute to a deeper understanding of how xenobiotics shape microbial ecosystems and their implications for human health.

Xenobiotics, human microbiome, gut microbiota, environmental pollutants, antibiotics, dysbiosis, microbial metabolism, probiotics, microbiome-based therapies