2024 Featured Articles
The 2024 collection of featured articles showcases groundbreaking research on overcoming cancer drug resistance. This year’s selection highlights key advances in understanding resistance mechanisms across various cancers, from the role of tumor-derived extracellular vesicles in endothelial cells to the regulation of Nrf2/Keap1 signaling in drug resistance. Emerging strategies, such as lipid-based nanomedicines, ALK inhibitors, and circular RNA targeting, offer new hope for overcoming therapeutic barriers. Additionally, insights into immune checkpoint inhibitors, chemoresistance, and the potential of combining genomics and epigenomics pave the way for next-generation cancer therapies. These articles provide essential perspectives for improving treatment outcomes in challenging cancers like colorectal, breast, and pancreatic cancers.
