fig3

Figure 3. Comparison of gut microbial diversity and composition between groups. (A) Shannon and Simpson diversity indexes and (B) score plot of PCoA (Bray-Curtis distance) of fecal microbiota of PD and PD-CI groups; (C) Differential taxa identified between the two groups of patients. Statistical differences were identified using Wilcoxon tests. Boxplots show median values with upper and lower quartiles. PD: PD patients with normal cognition; PD-CI: PD patients with cognitive impairment; PCoA: principal coordinate analysis.