fig2

Figure 2. Pediococcus acidilactici CCFM6432’s effect on alleviating depression symptoms. (A) Score change of the HADS; (B) Analysis of HADS subscales for depression and anxiety; (C) Score change of the SAS; (D) Score change of the PSQI; (E) Score change of the GSRS; (F) Factor analysis of the GSRS. Colors distinguish groups. ^**P < 0.01 in paired t-test. ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 in the unpaired t-tests. HADS: Hospital Anxiety and Depression Scale; SAS: Self-Rating Anxiety Scale; PSQI: Pittsburgh Sleep Quality Index; GSRS: Gastrointestinal Symptom Rating Scale.