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![Gut microbiota prevents small intestinal tumor formation due to bile acids in gnotobiotic mice](https://image.oaes.cc/afc8ceae-5ee9-4d08-a085-a3674da9c569/mrr3020.fig.1.jpg)
Figure 1. Phenotype of Apc1638N/+ mice after FMT. (A) Number of intestinal lesions for each donor-diet combination. Bottom: example macroscopic images of intestines with confirmed tumors. Left: multiple tumors (adenoma) in the PAR of a germfree mouse on the CA diet (red circle), with two additional intestinal lesions in the duodenum (red arrowheads). Right: A tumor (adenoma) in the ileum of a CTRL mouse on the CA diet (red arrowhead). Exemplary histological analyses of two lesions are shown in Supplementary Figure 5; (B) Number of lesions per gut region; (C) Length of the small intestine and colon (mean ± standard deviation). A previous version of this figure was published in the PhD thesis of Esther Wortmann (first author)[40]. In panels (A) and (B), the mean number of lesions is indicated by white lines. Statistics: Kruskal-Wallis followed by Dunn’s multiple comparisons with Benjamini-Hochberg adjustment