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Figure 2. The effect of Akk on intestinal-related diseases. Administration of Akk or its components to humans or mice can alleviate intestinal inflammation, tumors, and functional gastrointestinal diseases, as well as metabolic regulation such as alleviation of obesity, insulin resistance, and liver disease. Administering Akk or its components to humans or mice has been shown to reduce intestinal inflammation, inhibit tumor growth, and alleviate functional gastrointestinal disorders. Additionally, it contributes to metabolic regulation, including the reduction of obesity, improvement of insulin sensitivity, and mitigation of liver disease. Created with BioRender.com. Akk: Akkermansia muciniphila.