fig4

Figure 4. Volcano plot comparing the transcriptional response of A. muciniphila in fermentations containing a high concentration of GlcNAc (mid-log condition A) and mucin (condition D). Due to the high number of genes upregulated in high-GlcNAc, genes with a -log10P-value < 1 × 10^-50 and a log2 fold change < 2.5 that are mentioned in the text are not shown in this figure. All other differentially expressed genes mentioned in the text are labeled here. The complete overview of differentially expressed genes and their annotation can be found in Supplementary File 1. A. muciniphila: Akkermansia muciniphila; GlcNAc: N-acetylglucosamine.