fig4

Figure 4. Differential abundance of ASVs and species in demographic and clinical data and fecal characteristics. Heatmaps of all significantly (P < 0.05) differentially abundant (A) ASVs and (B) species in demographic and clinical data and fecal characteristics. Log₂ fold-change per unit of continuous variables or compared to a corresponding categorical variable is displayed. Additional taxonomic information is indicated at the family level. Significances were calculated using a log₂ transformed linear model with FDR correction for multiple testing. FAP-NOS: Functional abdominal pain-not otherwise specified; E2: enterotype 2; ASVs: amplicon sequence variants; FDR: false discovery rate.