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Figure 2. Influence of exercise on microbiome diversity. (A) Differences in alpha diversity between the variables “Athletes - Female” (Green), “Athletes - Male” (Orange), “Controls - Female” (Purple), and “Controls - Male” (Pink) values calculated using the Shannon and Simpson diversity metrics; (B) PCoA of beta diversity by intervention, measured by Bray-Curtis dissimilarity and calculated for species-level composition. Points are colored according to the variables “Athletes” (Green) and “Controls” (Orange); (C) Significant changes in the relative abundance of certain phylum across the population groups “Athletes” (Green) and “Controls” (Orange). The bounds, whiskers, and percentile of each box plot represented maximum, 75th percentile, median, 25th percentile, and minimum from the top to the bottom, respectively. PCoA: Principal coordinate analysis.