fig2
![<i>Bifidobacterium</i> and the intestinal mucus layer](https://image.oaes.cc/33bc28b6-e62b-4251-9974-fa3b9fbdc93e/mrr2037.fig.2.jpg)
Figure 2. Representative diagram of Bifidobacterium-goblet cell interactions. (A) Bifidobacterium species can generate acetate, which can elevate MUC2 expression and protein; (B) Bifidobacterium species can also generate varying levels of GABA, which can activate autophagy-driven expulsion of mucus. Through these mechanisms, Bifidobacteria are speculated to positively regulate goblet cells. GABA: B. dentium-generated gamma-aminobutyric acid.