fig1

Study of the binding of ΔFN3.1 fragments of the <i>Bifidobacterium longum</i> GT15 with TNFα and prevalence of domain-containing proteins in groups of bacteria of the human gut microbiota

Figure 1. Diagram illustrating the PFNA operon of B. longum subsp. longum GT15, and the FN3 protein and its fragments (∆FN3.1 protein, 2D FN3, CD FN3) used in our experiments aimed at testing the protein’s ability to bind the cytokine TNFα. The genes of the PFNA operon are pkb2 (serine-threonine protein kinase Pkb2, BLGT_RS02820, AIW43409.1), fn3 (fibronectin type III do-main-containing protein, BLGT_RS02815, AIW43408.1), aaa-atp (AAA-ATPase MoxR, BLGT_RS02810, AIW43407.1), duf58 (hypothetical protein with DUF58 domain, BLGT_RS02805, AIW43406.1), tgm (transglutaminase, BLGT_RS02800, AIW43405.1), prpC (protein phosphatase, BLGT_RS02795, AIW43404.1), hypothetical protein (BLGT_RS02790, AIW43403.1), fha (FHA do-main-containing protein, BLGT_RS02785, AIW43402.1). SP: signal peptide; TM: transmembrane.

Microbiome Research Reports
ISSN 2771-5965 (Online)

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