fig9
From: Mechanoimmunomodulation-based strategy on advancing tissue-engineered nanotopographic structures
Figure 9. The molecular structure and mechanosensing mechanism of Piezo1. (A) Top view of the molecular structure of Piezo1; (B) Side view of the molecular structure of Piezo1; (C) Piezo dimples the membrane into the cell, with the central channel structure closed (left panel), under low membrane tension. As membrane tension increases, the curved blades of Piezo flatten and the central channel structure opens (right panel). This figure is quoted with permission from Liang et al.[76].
