fig13
From: Mechanoimmunomodulation-based strategy on advancing tissue-engineered nanotopographic structures
Figure 13. Schematic diagram of disassembly/reassembly cycle of caveolae under different membrane tensions. Many signal transduction molecules can co-localize with caveolin proteins within caveolae. High membrane tension flattens caveolae into the membrane, resulting in the release of signaling components. Low membrane tension contributes to the formation of rosettes, while the loss of adhesion leads to the trafficking of caveolae. This figure is quoted with permission from Del Pozo et al.[120].
