fig10

Figure 10. Effect of Piezo1 deletion on proliferation and polarization of CD4⁺ T cells in vitro. (A and B) Piezo1 was not required for CD4⁺T cell proliferation; (C-F) Piezo1 does not affect T cell (T_H1 and T_H17) polarization; (G-L) Piezo1 modulates TGFβ signaling and restrains T_reg cells (***P < 0.001, ****P < 0.0001, ordinary one-way ANOVA with Sidak’s multiple comparisons, data are means ± SEM, n > 5 samples). This figure is quoted with permission from Jairaman et al.^[86].