fig1
From: Mechanoimmunomodulation-based strategy on advancing tissue-engineered nanotopographic structures
Figure 1. The schematic diagram of the cellular structural basis for generating mechanical forces. The cortical actin, formed by the loose organization of actin filaments, endows immune cells with mechanical strength. Integrins are important molecules in cell adhesion, linking the intracellular cytoskeleton to the extracellular matrix. Large assemblies of actin filaments in stress fibers, along with the myosin, enable the generation of contractility. Organizing actin filaments outward results in protrusive force.
