fig9

Figure 9. (A) Schematic illustration of using CuZn-N/C for in vivo microdialysis and online optical detection platform (OODP) to measure EP. (B) Time-dependent changes in light intensity reflecting the EP levels. (C) Comparison of the K_m of CuZn-N/C and LOD of OODP in different studies. (D and E), Selectivity (D) and stability (E) detection of EP using CuZn-N/C in the OODP. (F and G), Continuous monitoring of striatal EP levels before and after ischemia in the living rat brain using OODP, where (F) represents the saline group and (G) represents the drug administration group. Reprinted with permission from Ref.^[48], Copyright 2023, American Chemical Society.