fig3

Figure 3. Ivosidenib combined with cisplatin reduces colony formation and enhances apoptosis in ovarian cancer cells. (A) Quantification of cell colony number in SKOV3, CAOV3, and OVCAR4 cells treated with Ivosidenib, cisplatin, or their combination. Data represent mean ± SD of three biologically. ns, not significant, *P < 0.05; ***P < 0.001; ****P < 0.0001 using a two-way ANOVA followed by Tukey's post hoc test for multiple comparisons. (B) Quantification of cell apoptosis analysis in SKOV3, CAOV3, and OVCAR4 cells treated with 10 μM Ivosidenib, 10 μM cisplatin, or their combination for 72 h. Data represent mean ± SD of three biologically. ns, not significant, **P < 0.01; ***P < 0.001; ****P < 0.0001 using a one-way ANOVA followed by Tukey's post hoc test for multiple comparisons.