Webinar for "Gastrointestinal Stroma-Tumor (GIST)"

Dr. Ramadori studied Medicine in Perugia and Bologna, Italy. He joined Prof. Meyer zum Büschenfelde in Berlin and then in Mainz, Germany where he had his training in Internal Medicine, Gastroenterology and infectious diseases: There he also established primary cultures of liver cells, hepatocytes, Kupffer cells, endothelial cells and Ito-cells. For the establishment of the cell cultures of non-parenchymal cells, the help of the laboratory of Dr. Knook (the Netherlands) and its coworkers was of great importance. To study gene-expression at the molecular level, Dr. Ramadori moved to the laboratory of cell biology directed by Harvey Colten at the Children Hospital, Harvard University. There he spent an intensive period from 1984 to 1985 learning biosynthetic labeling of newly synthesized proteins, SDS-gel-electrophoresis RNA-isolation from cells and tissues, RNA analysis by Northern blot and cDNA-work. These techniques could then be applied in the study of cell-physiology and different animal models of inflammation damage repair and tumor development as well as in cancer diagnostic and immune cells study in the tumors of the human gastrointestinal tract. He became interested in pathology studies of liver tissue and tumor tissue from gastrointestinal tumors. As an internist, he was appointed as the Associate Editor of the pathology journal Laboratory Investigation by continuing his activity as a reviewer for other international journals. Dr. Ramadori was appointed (1992) as professor of medicine and director of Gastroenterology and Endocrinology with further responsibility for infectious diseases at the University clinic of Göttingen, Lower Saxony, Germany.