The journal concerns cancer metastasis and treatment, including the occurrence, development, progression, metastasis, and treatment of neoplastic diseases. Its coverage includes basic, translational and clinical studies related to cancer cell biology, genomics, precision medicine, medical oncology, radiation and immunotherapy and different types of solid and liquid cancers. Articles in the following areas are especially welcome:
- Basic research on cancer occurrence and progression, focusing on molecular biology, cell biology, and genetics;
- Mechanisms of metastasis and its prevention and control;
- Basic and clinical research on treatment of primary, metastatic tumors;
- Improved methods for medical, radiological, and/or surgical treatment of metastatic tumors (immunotherapy, chemotherapy, radiotherapy, biological therapy, operative treatment, interventional therapy, etc.);
- Observational/epidemiological studies focusing on environmental and behavioral factors that reduce the risk of cancer progression and metastasis and gene/environment interactions;
- Primary and secondary prevention studies.
To enhance the interdisciplinary scope of the journal and expand its coverage to include broader research areas, the journal proposes incorporating the following interdisciplinary researches:
- Bioinformatics and Computational Biology: Integrating computational methods to analyze large-scale datasets, such as genomic sequencing data, to identify biomarkers, therapeutic targets, and pathways involved in cancer metastasis and treatment response.
- Systems Biology Approaches: Utilizing systems biology approaches to understand the complex interactions between cancer cells, immune cells, stromal cells, and the tumor microenvironment in driving metastasis and therapeutic resistance.
- Nanotechnology and Drug Delivery: Exploring nanotechnology-based approaches for targeted drug delivery, imaging, and therapy monitoring in cancer treatment, with a focus on overcoming barriers to effective treatment of metastatic tumors.
- Immunotherapy and Immunology: Investigating the role of the immune system in cancer progression and metastasis, and exploring novel immunotherapeutic strategies, such as immune checkpoint inhibitors, CAR-T cell therapy, and cancer vaccines.
- Precision Oncology and Personalized Medicine: Advancing precision oncology approaches by integrating histopathological as well as molecular diagnostics, genomics, proteomics, and other omics technologies to tailor treatment strategies based on the individual genetic profile of patients and tumor heterogeneity.
- Biomedical Engineering and Medical Devices: Developing innovative medical devices and technologies for early detection, diagnosis, and treatment monitoring of metastatic cancer, including imaging modalities, biosensors, and minimally invasive surgical techniques.
- Psycho-Oncology and Behavioral Sciences: Investigating the psychosocial and behavioral factors influencing cancer progression, treatment adherence, and quality of life in patients with metastatic cancer, and developing interventions to support their emotional and psychological well-being.
- Environmental and Occupational Health: Examining the impact of environmental pollutants, occupational exposures, lifestyle factors, and socioeconomic determinants on cancer risk, progression, and metastasis, and identifying preventive measures to mitigate these risks.
- Regenerative Medicine and Tissue Engineering: Exploring regenerative medicine approaches to repair and regenerate tissues damaged by metastatic tumors or cancer treatments, including tissue-engineered constructs, stem cell therapy, and organoid models for drug screening.
- In vitro 3D cellular models (tumoroids, organoids, bioprinting) for studying the cancer growth, the tumor microenvironment, the invasiveness, and for drug screening as replacement of animal models.
- Bioethics and Health Policy: Addressing ethical considerations and policy implications of emerging technologies and interventions in cancer research and treatment, including issues related to access to care, patient autonomy, and informed consent.
JCMT publishes high-quality the Original Article, Review/Systematic Review, Meta-Analysis, Technical Note, Commentary, Editorial, Opinion, Perspective, Letter to Editor, etc.