Novel coronavirus infection and neuroinflammatory diseases

Prof. Le is the Director of the Academic Committee of School of Medicine of University of Electronic Science and Technology of China, Director of Neurology Department & Institute in Sichuan Academy of Medical Science-Sichuan Provincial Hospital. He also works as Tenured Professor & Head of the top clinical discipline in Dalian Medical University.

He was a Professor of Neurology and Director of the Parkinson's Disease Research Center at Baylor College of Medicine. He also worked as the Director of the Institute of Neurology at Shanghai Jiaotong University School of Medicine and the Executive Chairman of the Biomedical Institute of Shanghai Ruijin Hospital.

Prof. Le is interested in researching the pathogenesis, biomarkers, and targeted therapy of neurodegenerative diseases. He has published more than 300 papers in internationally critical academic journals, such as Nature Genetics, Science, PNAS, Autophagy, Brain, JAMA, Lancet Neurology, etc. The papers have been cited over 20,000 times, and he has been chosen into the list of Highly Cited Chinese Researchers in Neuroscience by Elsevier for eight years. Prof. Le held 3 Key Programs and 5 General Programs of the National Natural Science Foundation of China, held/participated in 4 Key Projects of Chinese National Programs for Fundamental Research and Development (973 programs) and Chinese National Programs for High Technology Research and Development (863 programs).

Yanjiang Wang, MD, Director of Neurology Department, Chief physician and professor, Daping Hospital, Army Military Medical University. Supported by the National Science Foundation for Outstanding Young People, he was selected as the special Professor of "Changjiang Scholars" of the Ministry of Education and the leading talent of the National "Ten Thousand Talents Plan". He is also a member of the Standing Committee of Neurology Society of Chinese Medical Association, Associate editor of Neuroscience Bulletin and director of Vas-Cog Asia. Clinical and scientific research directions are cognitive disorders related diseases. The corresponding author has published more than 100 papers in Nat Rev Neurol, Lancet Dis, JAMA Neurol, PNAS, Neurology and other journals, and participated in winning the second Prize of National Science and Technology Progress Award and the first prize of military and provincial level prizes. Journal of Alzheimer's Disease 20th Annual Alzheimer's Award.

Zhentao Zhang is a professor in the Department of Neurology, Renmin Hospital of Wuhan University. He is the vice director of the Hubei Neuropsychiatric Institute, and vice director of Department of Neurology in Renmin Hospital of Wuhan University. His research focuses on disease proteins that form pathological inclusions in neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease. His work demonstrated that fragmentation, modification by homocysteine and DOPEGEL, and other post-translational modifications of Tau and alpha-synuclein promote the aggregation and propagation of these pathologic proteins, leading to neurodegeneration. He is also interested in the molecular mechanisms underlying synaptic dysfunction and neuronal injury in neurodegenerative diseases. He has authored or co-authored over 80 professional publications in the field of neuroscience.

Professor and doctoral Supervisor. Winner of the National Outstanding Youth Fund, Tianjin Special Professor. He received his PhD in Neurology from Barrow Neurological Institute, USA, and completed post-doctoral research in immunology in Barrow as Tenure-Track Assistant Professor in Neurology. After returning to China, he worked in the Department of Neurology of Tianjin Medical University General Hospital, engaged in clinical and scientific research. He is currently the Deputy director of Tianjin Institute of Immunology, the Deputy director of Tianjin Institute of Neurology, the director of Neurodegenerative Diseases Research Department, the member of the Cerebrovascular Disease Group of the Neurology Branch of the Chinese Medical Association, and the Standing member of the Neuroimmunology Group of the Chinese Society of Immunology. Clinical and scientific research focuses on immune mechanisms and clinical interventions in brain diseases. Representative research results have been published as corresponding authors in journals such as Cell, Nature Neuroscience, Immunity and Science Translational Medicine. By Nature Neuroscience, Immunity, Science Immunology and other journals special article introduction. He is on the editorial board of Fundamental Research, Ageing & Neurodegenerative Diseases. He received the American Heart Association (AHA) Scientist Development Award, the Chinese Stroke Society "Best Citation Award", "Tianjin Natural Science First Prize" and other awards.

Prof. Sheng Chen is deputy director, professor, also American Certificated Physician, and works in Department of Neurology, Ruijin Hospital, and Shanghai Jiaotong University School of Medicine. He is a committee member of Neuroimmunology Committee of Chinese Medical Association, American and Chinese Society of Neuroscience and Neurology. His main research focus is neuro-immunology and neuro-degenerative diseases. He had published more than 60 SCI articles including in Lancet Neurology, JAMA Neurology, ElinicalMedicine, Neurology, Autophagy, Molecular Neurodegeneration, European Journal of Neurology, and Brain Pathology. He also acquired the support of both National Natural Sciences Foundation of China and Shanghai Science and Technology Project.