Topic: Cancer Stem Cells: Impact on Treatment

It is generally believed that the small population of the intratumoral carcinoma stem cells (CSCs) is responsible for poor clinical outcome, because CSCs are considered as a reason for the tumor heterogeneity, diminished sensitivity to chemo- and radiotherapy and enhanced abilities for metastatic spread. Investigation of the biological properties of CSCs is a hot topic in cancer research. In order to know more about CSC behavior, it is necessary to possess the CSC-specific molecular patterns distinguishing CSCs from non-CSCs.