Topic: ABC Transporters in Multidrug-Resistant Cancer
Guest Editor
Special Topic Introduction
ABC transporters, such as P-glycoprotein and ABCG2, are known to confer multidrug resistance (MDR) in cancer, thus rendering previously sensitive cancer cells multi-resistant to a large range of chemically unrelated compounds.
The aim of this Special Issue is to sum up the latest knowledge on the role and function of ABC transporters in cancer.
Specifically, the latest development on the following topics will be reviewed:
- The mechanisms of MDR and the implications for clinical drug resistance.
- How cancer cells increase MDR1 (ABCB1) expression.
- Evidence for the importance of ABC transporters in cancer.
- Regulation of the expression and trafficking of ABCG2.
- Defeating multidrug resistance in cancer: a new twist on an old story.
The aim of this Special Issue is to sum up the latest knowledge on the role and function of ABC transporters in cancer.
Specifically, the latest development on the following topics will be reviewed:
- The mechanisms of MDR and the implications for clinical drug resistance.
- How cancer cells increase MDR1 (ABCB1) expression.
- Evidence for the importance of ABC transporters in cancer.
- Regulation of the expression and trafficking of ABCG2.
- Defeating multidrug resistance in cancer: a new twist on an old story.
Keywords
Multidrug resistance, ABC transporters, cancer, drug resistance, P-glycoprotein, ABCG2
Submission Deadline
20 Nov 2020
Submission Information
For Author Instructions, please refer to https://www.oaepublish.com/cdr/author_instructions
For Online Submission, please login at https://www.oaecenter.com/login?JournalId=cdr&IssueId=cdr201120446
Submission Deadline: 20 Nov 2020
Contacts: Chloe Yang, Assistant Editor, [email protected]
Bill Li, Managing Editor, [email protected]
