fig5

Figure 5. (A) Drug release profiles at different pH (n = 3)^[91]. Copyright 2020, ACS Publications; (B) In vitro release profile of DOX from hydrogel-2 in PBS (0.01 M) at pH 7.4, 6.5 and 5.0 under 37 °C, and attached images of DOX-loaded hydrogels after incubation for 168 h^[102]. Copyright 2017, Elsevier; (C) Photothermal and electrical stimulation release chemotherapeutics from hydrogel for apoptosis induction in tumor cells^[103]. Copyright 2020, ACS Publications; (D) Releasing profiles of insulin from the ConA@poly(NIPAM) nanogels in the presence of 0.0 mM ((the prmM ((the prmM ((the premM ((the premM (◄), and 20.0 mM (►) glucose in PBS of 7.4 at 37 °C. In the blank release (◊), the insulin solution was released to the PBS^[105]. Copyright 2014, RSC Publishing; (E) Insulin released in D-PBS under different conditions^[104]. Copyright 2018, Wiley. DOX: Doxorubicin; PBS: phosphate-buffered saline; D-PBS: Dulbecco’s phosphate-buffered saline.