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From: Stimuli-responsive hydrogel actuators for skin therapeutics and beyond

Figure 3. (A) Skin wounds of chicken embryo. AAD responds to skin temperature and promotes wound healing through active contraction^[93]. Copyright 2019, AAAS; (B) Schematic of the nanocomposite dressing fabrication and the synergistic treatment of a bacterium infected wound^[94]. Copyright 2020, RSC Publishing; (C) PH-responsive drug delivery of HAO from protamine NPs/HAO CaAlg hydrogel for a period of 8 h under different pH conditions^[95]. Copyright 2019, Springer; (D) The schematic diagram of structure, pH and glucose-responsive mechanism of PC hydrogel and its application in diabetic foot ulcers and athletic wound healing. PH and glucose-responsive metformin release^[96]. Copyright 2022, ACS Publications. AAD: Active adhesive dressings; HAO: hyaluronan oligosaccharides; NPs: nanoparticles; PC: PEGS-PBA-BA/CS-DA-LAG.