fig4

Figure 4. Hematoxylin and eosin staining of liver sections of 8-week tamoxifen-induced control (A) and kindlin-2-deleted (B) mice. The controls displayed normal bile ducts, whereas the knockout mice exhibited the characteristic onion-skin type of fibrosis around the bile ducts. Space bare are 100 µm. BD: Bile duct; PA: portal artery; PV: portal vein.