fig6
From: The NOAEL equivalent for the cumulative body burden of cadmium: focus on proteinuria as an endpoint
Figure 6. BMDL and BMDU of ECd/Ccr producing a 10% reduction in eGFR. BMDL and BMDU bounds of the 95%CI of BMD with a 10% reduction in eGFR were based on (A) exponential, (B) Hill, (C) inverse exponential and (D) natural logarithmic dose-response models. (E-G) BMDL and BMDU values were obtained by bootstrap model weighting and averaging with 200 repeats. BMDL: Benchmark dose lower; BMDU: benchmark dose upper; eGFR: estimated glomerular filtration rate; CI: confidence interval.
