fig3

Figure 3. BMDL₅ values of E_Cd/E_cr for proteinuria and low eGFR. Bootstrap model weighting and averaging of BMDL and BMDU bounds of the 95%CI of BMD for (A-C) 5% prevalence of proteinuria and (D-F) 5% prevalence of low eGFR. BMDL₅ and BMDU₅ values of E_Cd/E_cr were based on two-stage, logarithmic logistic, Weibull, logarithmic probability, gamma, exponential and Hill dose-response models. BMDL: benchmark dose lower; eGFR: estimated glomerular filtration rate; BMDU: benchmark dose upper; CI: confidence interval.