fig2

Figure 2. Conformational states of relaxed myosin. In the disordered relaxed state (DRX), myosin heads are in a high adenosine triphosphate (ATP)-consuming unstable state. In the super-relaxed state (SRX), myosin heads are folded onto the myosin backbone and consume tenfold lower amounts of ATP. Created in BioRender. Nollet E (2025) https://BioRender.com/p5fg70j.