fig6

Figure 6. Schemes of the nucleic acid-based timing network driven by different enzymatic nucleic acid reactions: (A) RNase H-driven digestion of RNA blocker in RNA-DNA hybrid duplex; (B) Fpg-induced decomposition of DNA blocker containing deoxyuridine mutations; (C) UDG-guided degradation of Uracil-modified DNA blocker. (D) Orthogonal timing operation of strand-displacement reactions by three enzymes. This figure is quoted with permission from Bucci et al.^[122].