fig1
![Direct construction of <i>d</i><sub><i>3</i></sub>-methylated all-carbon quaternary stereocenters through carbene-catalyzed desymmetrization](https://image.oaes.cc/9f92960f-7fc6-4047-94c0-f6600db554e5/CS-2023-4.fig.1.jpg)
Figure 1. Asymmetric desymmetrization of d3-methylated cyclic 1,3-diketones; (a) Representative examples containing CD3; (b) Naturally occurring and biologically active molecules with methylated all-carbon quaternary stereocenters; (c) This work: NHC-catalyzed asymmetric desymmetrization of d3-methylated 1,3-diketones.