fig5

Breast cancer cell resistance to hormonal and targeted therapeutics is correlated with the inactivation of the NR6A1 axis

Figure 5. (A) Methylation in the CpG island, N-Shore, and N-Shelf sequences at the NR6A1 locus in MCF-7, MCF-7/T, MCF-7/Rap, and MDA-MB-231 cells. **P < 0.01, ****P < 0.0001 (t-test was used to compare two sample means); (B) Correlation between NR6A1 expression and methylation for cg14156446 (TCGA-BRCA dataset: 853 cases).

Cancer Drug Resistance
ISSN 2578-532X (Online)

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