fig4

Figure 4. (A) The expression of NR6A1 in the MCF-7 cells after NR6A1 knockdown; ^****P < 0.0001. The MCF-7/SCR and MCF-7/shNR6A1 cell line sensitivity to tamoxifen (B) and rapamycin (C); ^*P < 0.05 - compared to cells exposed to empty vector. The data reflect the mean ± S.D. from three independent trials; (D) RT-PCR analysis of DNMT3A expression in MCF-7 cell line after NR6A1 knockdown; ^***P < 0.05.