fig2

The uniqueness of ABCB5 as a full transporter ABCB5FL and a half-transporter-like ABCB5β

Figure 2. Tissue and intracellular localization of ABCB5FL and ABCB5β. (A) Representation of human ABCB5 tissue localization based on ABCB5FL and ABCB5β mRNA detection from[1,6,18]. Light blue represents ABCB5β localization. Dark blue represents ABCB5FL localization; (B) Schematic representation of the proposed intracellular localization of ABCB5β in light blue[2,19,20] and one of the two longest isoforms in gray[21]. Results obtained using antibodies, for which more validation is necessary, are highlighted by a pink antibody. Results obtained with tagged protein are highlighted by a green round schematizing a GFP tag. PM: Plasma membrane; ER: endoplasmic reticulum; PL: phagolysosomes; GFP: green fluorescent protein.

Cancer Drug Resistance
ISSN 2578-532X (Online)

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