fig2
Figure 2. Signaling pathways regulating the activity and levels of MITF, a key transcription factor. MITF: Microphthalmia-associated transcription factor; PD-L1: programmed death-ligand 1; PI3K: phosphoinositide 3-kinase; ATF3/CCL4: activating transcription factor 3/macrophage inflammatory protein-1 beta; Wnt: signaling proteins; GF: growth factor receptor.
