fig1

The BET inhibitor sensitivity is associated with the expression level of CDC25B in pancreatic cancer models

Figure 1. PDX models of PDAC have contrasting levels of CDC25B protein. (A) IHC of 20 PDAC PDX models shows that the models express different levels of CDC25B; (B) Bar graph depicting the number of tumors with low, moderate or high level CDC25B; (C) IHC staining for CDC25B in PA16 or PA18 PDAC PDX tumor models. Expression indices are shown in the left bottom corner of each image. The tumor sections were counterstained with H&E. Bar = 10 µm. PDX: Patient-derived xenograft; PDAC: pancreatic ductal adenocarcinoma; CDC25B: cell division cycle 25B; IHC: immunohistochemistry; H&E: hematoxylin and eosin.

Cancer Drug Resistance
ISSN 2578-532X (Online)

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