fig7

Screening of photosensitizers-ATP binding cassette (ABC) transporter interactions <i>in vitro</i>

Figure 7. ABCG2-overexpressing cells transport selected photosensitizers (BPD and Rose Bengal). Flow cytometry was performed to assess the intracellular fluorescence of photosensitizer. The raw mean fluorescence intensity values are reported for individual histograms. BPD and Rose bengal show higher uptake in the presence of the ABCG2 inhibitor, FTC. NT: Not treated, control; PS: photosensitizer only; PS+Inhibitor: photosensitizer + FTC; BPD: benzoporphyrin derivative; FTC: fumitremorgin C.

Cancer Drug Resistance
ISSN 2578-532X (Online)

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