fig6
Figure 6. Intracellular levels of photosensitizers in MRP1-overexpressing MCF-7/VP cell line using extraction method. Intracellular levels of the photosensitizers from cell lysates were determined by the fluorescence signals of the photosensitizer. Rose bengal shows a significant increase in accumulation in MCF-7/VP cells in the presence of MRP1 inhibitor (MK571). The fmole/mg protein of photosensitizer is plotted for all the experimental groups. (A) Benzoporhyrin derivative; (B) Temoporfin; (C) Redaporfin; (D) Talaporfin sodium; (E) Methylene blue; (F) Indocyanine green; (G) Rose bengal. *P < 0.05, **P < 0.01, ***P < 0.001; One-way ANOVA Tukey’s range test
