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Figure 2. Association analysis of BRAF mutations with molecular and clinical outcomes in CRC and NSCLC. (A) OS in CRC patients carrying (red line) or not (blue line) BRAF mutations on Kaplan-Meier graphs; (B) Patterns of MSI and (C) CIMP in BRAF-mutated and -unaltered CRCs; (D) OS in NSCLC patients carrying (blue line) or not (red line) BRAF mutations on Kaplan-Meier graphs; (E) Incidence of specific tumor forms and (F) TMB in BRAF-mutated and -unaltered NSCLCs. CRC: Colorectal cancer; NSCLC: non-small cell lung carcinoma; OS: overall survival; MSI: microsatellite instability; CIMP: CpG island methylator phenotype; TMB: tumor mutational burden; MSS: microsatellite stable.