fig5

Fibroblast growth factor receptor alterations and resistance mechanisms in the treatment of pediatric solid tumors

Figure 5. Alteration frequencies of FGFR genes in Ewing sarcoma and neuroblastoma. Queries and resulting figures were generated in cBioPortal (http://www.cbioportal.org) by searching “sarcoma” and “neuroblastoma” and selecting all pediatric cancer studies and querying by FGFR1, FGFR2, FGFR3, and FGFR4, with (A) FGFR3 and (B) FGFR4 gene alteration frequencies and absolute counts for Ewing sarcoma are shown. No mutations or other gene variations were found for the FGFR1 and FGFR2 genes in Ewing sarcoma samples. (C) FGFR1, (D) FGFR2, (E) FGFR3, and (F) FGFR4 gene alteration frequencies for neuroblastoma tumors from cBioPortal are shown. FGFR: fibroblast growth factor receptor.

Cancer Drug Resistance
ISSN 2578-532X (Online)

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