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Figure 1. Prevalence of targetable FGFR signaling pathway alterations in pediatric cancers. Queries and resulting figures were generated in cBioPortal (http://www.cbioportal.org) by searching Pediatric Cancer Studies and querying by FGFR1, FGFR2, FGFR3, FGFR4, IDH1, IDH2, KRAS, ALK, ROS1, NTRK1, NTRK2, NTRK3, BRAF, and EGFR, with the resulting OncoPrint for identified mutations, amplifications, and deletions shown (A). (B) FGFR1, FGFR2, FGFR3, and FGFR4 gene alteration frequency (B) and absolute counts (C) by pediatric cancer type from cBioPortal are shown. FGFR: fibroblast growth factor receptor.