fig1
Figure 1. TAMs or MDSCs are considered to be important promoters of the TME. These cells can secrete cytokines, such as TGF-β, which activate primary-derived inflammatory pathways in the TME. Additionally, Treg cells and extracellular adenosine can promote immunosuppression. Figure was created with Biorender.com. TAMs: Tumor-associated macrophages; MDSCs: myeloid-derived suppressor cells; TME: tumor microenvironment; TGF-β: transforming growth factor-beta; Treg: regulatory T; M2 mø: M2 macrophages.
