fig9
From: Reprogrammed lipid metabolism in advanced resistant cancers: an upcoming therapeutic opportunity
Figure 9. Competition for FA utilization between immune and tumor cells. Cancer cells compete with immune cells for FA uptake. FA uptake promotes FAO, which supports cell growth and resistance to treatment. PHD3 inhibits mitochondrial FA uptake. Created with BioRender.com. FA: fatty acid; FAO: β-fatty acid oxidation; PHD3: prolyl hydroxylase 3.