fig8

Figure 8. Effect of pentoxifylline in combination with different anticancer drugs on the percentage of cell growth of NCI-H460 and NCI-H460/R cell lines, assessed by the SRB assay. Cells were treated for 48 h with pentoxifylline at 1.0 mM and (A) paclitaxel at 5.7 nM, (B) carboplatin at 17.7 µM, (C) vinorelbine at 35 nM, and (D) vinorelbine at 35 nM plus carboplatin at 17.7 μM. The effect of the vehicle at the highest concentration was also tested. Data are presented as a percentage of cell growth. ^*,#P ≤ 0.05; ^**,##P < 0.01; ^***,###P < 0.001; ^****,####P < 0.0001; ns: P > 0.05. SRB: Sulforhodamine B.