fig5

Figure 5. Effect of 48 h treatment with 1 or 2 mM pentoxifylline on the percentage of cell death of (A) sensitive NCI-H460 and (B) MDR NCI-H460/R NSCLC cells, determined by flow cytometry. The effect of the vehicle at the highest concentration was also tested. The frequency of dead cells for each condition (top panels) and the representative dot plot histograms (bottom panels) are shown. ^*P ≤ 0.05. MDR: Multidrug resistance; NSCLC: non-small cell lung cancer.