fig2
Figure 2. Effect of 48-h treatment with 1 mM pentoxifylline on the expression levels of CHI3L1 and its downstream proteins (β-Catenin, p-Akt and p-ERK), determined by Western Blot on (A-D) NCI-H460 vs. NCI-H460/R and on (E-H) A549 vs. A549-CDR2 cell lines. The effect of the vehicle (H2O) was also analyzed. β-Actin was used as a loading control. Data are presented as a percentage of expression. *P ≤ 0.05. CHI3L1: Chitinase 3-like-1; ERK: extracellular signal-regulated kinase.
