fig9

Isocucurbitacin B inhibits glioma growth through PI3K/AKT pathways and increases glioma sensitivity to TMZ by inhibiting hsa-mir-1286a

Figure 9. (A) Prognosis of low and high expression levels of hsa-mir-1286a in grade 4 gliomas; (B) Expression of hsa-mir-1286a was detected using RT-qPCR (*P < 0.05, **P < 0.01 vs. control group); (C) Expression of hsa-mir-1286a after using hsa-miR-1286a inhibitor was detected using RT-qPCR (**P < 0.01 vs. control group); (D) Cell viability of U251 cells after 24 h of TMZ treatment after microFF hsa-miR-1286 inhibitor added (****P < 0.0001 vs. control group). RT-qPCR: Reverse transcription-quantitative polymerase chain reaction; TMZ: temozolomide.

Cancer Drug Resistance
ISSN 2578-532X (Online)

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